Severe apnoeas following immunisation in premature infants

Arch Dis Child Fetal Neonatal Ed. 1999 Jul;81(1):F67-8. doi: 10.1136/fn.81.1.f67.

Abstract

Four premature infants developed apnoeas severe enough to warrant resuscitation after immunisation with diphtheria, pertussis, and tetanus (DPT), and Haemophilus influenzae B (Hib). One required re-intubation and ventilation. Although apnoeas after immunisation are recognised, they are not well documented. It is time for further research to elucidate the best time to immunise such infants.

Publication types

  • Case Reports

MeSH terms

  • Apnea / etiology*
  • Bacterial Capsules
  • Diphtheria-Tetanus-Pertussis Vaccine / adverse effects*
  • Female
  • Gestational Age
  • Haemophilus Vaccines / adverse effects*
  • Humans
  • Immunization / adverse effects*
  • Infant, Newborn
  • Infant, Premature*
  • Male
  • Polysaccharides, Bacterial / adverse effects*
  • Time Factors

Substances

  • Diphtheria-Tetanus-Pertussis Vaccine
  • Haemophilus Vaccines
  • Haemophilus influenzae type b polysaccharide vaccine
  • Polysaccharides, Bacterial