Pseudolymphoma syndrome due to carbamazepine

J Dermatol. 1999 May;26(5):329-31. doi: 10.1111/j.1346-8138.1999.tb03480.x.

Abstract

We described a 29-year-old Japanese woman with a pseudolymphoma syndrome due to carbamazepine. Physical examination revealed a diffuse erythematous papular eruption over almost all of her body with generalized lymphadenopathy. Histopathologic examination disclosed histology compatible with the nodular pattern of pseudo-T-cell lymphoma. The Southern blot analysis did not disclose the monoclonality of the gamma T cell recepter gene. We consider that it is very important to recognize this pseudolymphoma syndrome due to carbamazepine to avoid possibly subjecting the patient to unnecessary chemotherapy.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antimanic Agents / adverse effects*
  • Antimanic Agents / therapeutic use
  • Blotting, Southern
  • Carbamazepine / adverse effects*
  • Carbamazepine / therapeutic use
  • Diagnosis, Differential
  • Facial Dermatoses / chemically induced*
  • Facial Dermatoses / pathology
  • Female
  • Humans
  • Pseudolymphoma / chemically induced*
  • Pseudolymphoma / pathology
  • Schizophrenia / drug therapy*
  • Skin Diseases / chemically induced*
  • Skin Diseases / pathology
  • Syndrome

Substances

  • Antimanic Agents
  • Carbamazepine