Guiaflavine, a new bisindole quaternary alkaloid from the stem bark of Strychnos guianensis

J Nat Prod. 1999 Jun;62(6):898-900. doi: 10.1021/np9804738.

Abstract

A reinvestigation of Strychnos guianensis resulted in the isolation of a colored quaternary bisindole alkaloid from the stem bark. The structure of this new substance, guiaflavine (1), was defined by detailed spectroscopic methods and comparison with model compounds.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chromatography, Thin Layer
  • Indoles*
  • Male
  • Mice
  • Plant Extracts / chemistry
  • Quinolizines / isolation & purification*
  • Quinolizines / toxicity
  • South America
  • Spectrophotometry, Infrared
  • Spectrophotometry, Ultraviolet
  • Spectroscopy, Fourier Transform Infrared
  • Strychnine / analogs & derivatives*
  • Strychnine / isolation & purification
  • Strychnine / toxicity
  • Trees*

Substances

  • Indoles
  • Plant Extracts
  • Quinolizines
  • guiaflavine
  • Strychnine