A polyisoprenylated benzophenone from Cuban propolis

J Nat Prod. 1999 Jul;62(7):1013-5. doi: 10.1021/np980339n.

Abstract

A novel polyisoprenylated benzophenone (1) has been isolated from an ethanol extract of Cuban propolis. Its structure has been determined using high-field 2D NMR techniques. Compound 1 showed significant antimicrobial and antifungal activity against a variety of bacteria and yeasts.

MeSH terms

  • Anti-Bacterial Agents
  • Anti-Infective Agents / chemistry
  • Anti-Infective Agents / isolation & purification*
  • Antifungal Agents / chemistry
  • Antifungal Agents / isolation & purification*
  • Bacteria / drug effects
  • Benzophenones / chemistry
  • Benzophenones / isolation & purification*
  • Chromatography, High Pressure Liquid
  • Cuba
  • Magnetic Resonance Spectroscopy
  • Microbial Sensitivity Tests
  • Propolis / chemistry*
  • Spectrophotometry, Infrared
  • Yeasts / drug effects

Substances

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Antifungal Agents
  • Benzophenones
  • polyisoprenyl benzophenone
  • Propolis