The diagnosis of freemartinism in cattle using sex-specific DNA sequences

Res Vet Sci. 1999 Aug;67(1):111-2. doi: 10.1053/rvsc.1998.0286.

Abstract

The majority of heifers born co-twins to bulls are infertile freemartins. It is important that the condition be diagnosed at an early age as freemartins have no potential for use as replacement stock. A rapid, robust, reliable technique for freemartin diagnosis is described. Three Y-specific polymerase chain reaction (PCR) primer pairs: BOV97M, BRY.1 and AMX/Y were used to detect male cells in the blood of heifers born co-twins to bulls. PCR -based tests have advantages over currently used methods of freemartin diagnosis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Base Sequence
  • Cattle
  • DNA / chemistry*
  • Female
  • Freemartinism / diagnosis
  • Freemartinism / genetics*
  • Male
  • Molecular Sequence Data

Substances

  • DNA