Abstract
This study shows an increase in von Willebrand factor antigen in blood collected from the coronary sinus shortly after coronary angiography with an ionic contrast agent (diatrizoate), but not a nonionic contrast agent (iohexol). These findings suggest that ionic contrast agents may cause more endothelial injury than nonionic contrast agents.
Publication types
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Comparative Study
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Contrast Media / pharmacology*
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Coronary Angiography / methods*
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Coronary Disease / blood
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Coronary Disease / diagnostic imaging*
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Diatrizoate / pharmacology
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Female
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Humans
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Iohexol / pharmacology
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Male
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Middle Aged
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von Willebrand Factor / analysis*
Substances
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Contrast Media
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von Willebrand Factor
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Diatrizoate
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Iohexol