[Myocardial perfusion scintigraphy with 99mTC-sestamibi and gated SPECT and myocardial perfusion scintigraphy with reinjection of 201Tl at 24 hours. Are the techniques comparable?]

Rev Esp Med Nucl. 1999 Jun;18(3):169-75.
[Article in Spanish]

Abstract

Aim: To compare the results obtained with 99mTc-sestamibi and gated-SPECT (gated SPECT in stress and rest) with 201Tl (stress, redistribution, and 24 hour reinjection SPECT).

Methods: Twenty patients underwent two SPECT studies, one with 201Tl and the other with 99mTc-sestamibi.

Results: Using 201Tl as a reference, 177 segments were considered normal, 31 viable and 32 with myocardial necrosis. The overall concordance with 99mTc-sestamibi was 84.2%. In the subgroup of defects that improved after reinjection of 201Tl, it was much less (45%), even after wall thickness and movement (55%) were analyzed.

Conclusion: The overall concordance between 201Tl scintigraphy compared to 99mTc-sestamibi is acceptable. Correlation is low in the viable segments with 99mTc-sestamibi, even after analyzing the Gated-SPECT.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Data Interpretation, Statistical
  • Electrocardiography
  • Exercise Test
  • Female
  • Gated Blood-Pool Imaging*
  • Hemodynamics
  • Humans
  • Male
  • Middle Aged
  • Myocardial Infarction / diagnosis
  • Myocardial Infarction / diagnostic imaging*
  • Myocardial Infarction / physiopathology
  • Radiopharmaceuticals
  • Technetium Tc 99m Sestamibi
  • Thallium Radioisotopes / administration & dosage
  • Time Factors
  • Tomography, Emission-Computed, Single-Photon* / methods

Substances

  • Radiopharmaceuticals
  • Thallium Radioisotopes
  • Technetium Tc 99m Sestamibi