Monosomy 22 and trisomy 14 may be early events in the tumorigenesis of adult granulosa cell tumor

I Van den Berghe; P Dal Cin; K De Groef; P Michielssen; H Van den Berghe

doi:10.1016/s0165-4608(98)00249-0

Monosomy 22 and trisomy 14 may be early events in the tumorigenesis of adult granulosa cell tumor

Cancer Genet Cytogenet. 1999 Jul 1;112(1):46-8. doi: 10.1016/s0165-4608(98)00249-0.

Authors

I Van den Berghe¹, P Dal Cin, K De Groef, P Michielssen, H Van den Berghe

Affiliation

¹ Center for Pathology, University of Leuven, Belgium.

PMID: 10432935
DOI: 10.1016/s0165-4608(98)00249-0

Abstract

The finding of monosomy 22 and trisomy 14 in a case of adult type of granulosa-thecoma cell tumor and the available information from the literature allow for the hypothesis that, especially monosomy 22, but also trisomy 14, may be early events in the tumorigenesis of adult sex cord-stromal tumors in general, and of granulosa-thecoma cell tumors in particular.

Publication types

Case Reports

MeSH terms

Adolescent
Adult
Aged
Child
Chromosomes, Human, Pair 14*
Chromosomes, Human, Pair 22*
Female
Granulosa Cell Tumor / genetics*
Humans
Karyotyping
Middle Aged
Monosomy*
Trisomy*