Integrated high-resolution BAC, P1, and transcript map of the CHH region in chromosome 9p13

Genomics. 1999 Aug 1;59(3):319-25. doi: 10.1006/geno.1999.5883.

Abstract

A bacterial artificial chromosome (BAC) and P1 contig of the proximal part of chromosome 9p centromeric of markers D9S165 and D9S304 is described. This 1.1- to 1.7-Mb portion of chromosome 9p13 was previously not physically mapped. It contains 24 genes or expressed sequence tags, five polymorphic AC repeats, and three new polymorphic single-strand conformation polymorphism variants. Several of the genes thus mapped are excellent candidates for disease-causing genes whose loci have previously been assigned to proximal 9p. Our primary interest is in the cartilage-hair hypoplasia gene (CHH) that resides within the contig between markers D9S163 and D9S1791 based on linkage evidence.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Base Sequence
  • Cartilage Diseases / genetics
  • Chromosome Mapping
  • Chromosomes, Bacterial
  • Chromosomes, Human, Pair 9*
  • Contig Mapping
  • Expressed Sequence Tags
  • Genetic Markers
  • Hair Diseases / genetics
  • Humans
  • Molecular Sequence Data
  • Osteochondrodysplasias / genetics*
  • Polymorphism, Genetic
  • Polymorphism, Single-Stranded Conformational

Substances

  • Genetic Markers

Associated data

  • GENBANK/AF124861
  • GENBANK/AF124862
  • GENBANK/AF124863
  • GENBANK/AF124864
  • GENBANK/AF124865
  • GENBANK/AF124866
  • GENBANK/AF124867
  • GENBANK/AF124868
  • GENBANK/AF124869
  • GENBANK/AF124870
  • GENBANK/AF124871
  • GENBANK/AF124872
  • GENBANK/AF124873
  • GENBANK/AF124874
  • GENBANK/AF124875
  • GENBANK/AF124876
  • GENBANK/AF124877
  • GENBANK/AF124878
  • GENBANK/AF124879
  • GENBANK/AF124880
  • GENBANK/AF124881
  • GENBANK/AF124882
  • GENBANK/AF124883
  • GENBANK/AF124884
  • GENBANK/AF124885
  • GENBANK/AF124886
  • GENBANK/AF124887
  • GENBANK/AF124888
  • GENBANK/AF124889
  • GENBANK/AF124890