Idiopathic hypoparathyroidism associated with adult rheumatoid arthritis

Clin Rheumatol. 1999;18(4):334-6. doi: 10.1007/s100670050112.

Abstract

A 48-year-old female patient with adult onset idiopathic hypoparathyroidism diagnosed at the age of 28 years developed a typical seropositive rheumatoid arthritis (RA) at 46 years of age after several years of evolution of a palindromic rheumatism. Only one case of an association between idiopathic hypoparathyroidism and RA has been described in the medical literature. Autoimmunity seems to play a pivotal role in the aetiopathogenesis of both diseases, and could explain the nature of this association; nevertheless, a chance association could not be excluded.

Publication types

  • Case Reports

MeSH terms

  • Absorptiometry, Photon
  • Alleles
  • Antibodies, Antinuclear / analysis
  • Arthritis, Rheumatoid / diagnostic imaging
  • Arthritis, Rheumatoid / etiology*
  • Arthritis, Rheumatoid / immunology
  • Arthritis, Rheumatoid / metabolism
  • Bone Density
  • Calcium / blood
  • Diagnosis, Differential
  • Female
  • Follow-Up Studies
  • HLA-DR Antigens / genetics
  • HLA-DR Antigens / immunology
  • HLA-DRB1 Chains
  • Humans
  • Hypoparathyroidism / complications*
  • Hypoparathyroidism / diagnostic imaging
  • Hypoparathyroidism / immunology
  • Hypoparathyroidism / metabolism
  • Middle Aged
  • Parathyroid Hormone / blood

Substances

  • Antibodies, Antinuclear
  • HLA-DR Antigens
  • HLA-DRB1 Chains
  • Parathyroid Hormone
  • Calcium