Models of cell cycle control in eukaryotes

J Biotechnol. 1999 May 28;71(1-3):239-44. doi: 10.1016/s0168-1656(99)00027-9.

Abstract

The molecular mechanisms of cell cycle control are now known in enough detail to warrant mathematical modeling by kinetic equations. Despite the repetitive nature of the cell division cycle, the most appropriate models emphasize steady-state solutions rather than limit cycle oscillations, because cells progress toward division by passing a series of checkpoints (steady states).

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Cell Cycle*
  • Eukaryotic Cells / physiology*
  • Mathematics
  • Models, Biological*