Long-term sequelae of spontaneous axillary-subclavian venous thrombosis

Ann Intern Med. 1999 Oct 5;131(7):510-3. doi: 10.7326/0003-4819-131-7-199910050-00006.

Abstract

Background: The frequency and severity of post-thrombotic sequelae after spontaneous axillary-subclavian venous thrombosis remain poorly known.

Objective: To determine the late sequelae of conventionally treated spontaneous axillary-subclavian venous thrombosis.

Design: Cross-sectional study.

Setting: University department of vascular medicine.

Patients: 54 patients seen during an 18-year period (mean follow-up, 5 years).

Measurements: Scores for the severity of post-thrombotic symptoms were graded on a numerical rating scale ranging from 0 to 10 and on a 6-point verbal rating scale. Ultrasonographic sequelae were classified as grade 0, normal flow; grade 1, moderate obstruction; or grade 2, severe obstruction or occlusion.

Results: Verbal scores were "nil/negligible" in 47% of patients and "severe/intolerable" in 13%; numerical scores were 0 to 3 in 78% of patients and 7 to 10 in 9%. Grade 2 ultrasonographic sequelae were found in 22% of cases. No relation was seen between ultrasonographic sequelae and symptom severity scores.

Conclusion: The overall clinical outcome of spontaneous axillary-subclavian venous thrombosis is good, and there is no relation between the severity of late symptoms and ultrasonographic sequelae.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Anticoagulants / therapeutic use*
  • Axillary Vein* / diagnostic imaging
  • Axillary Vein* / physiopathology
  • Cross-Sectional Studies
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Regional Blood Flow / physiology
  • Subclavian Vein* / diagnostic imaging
  • Subclavian Vein* / physiopathology
  • Treatment Outcome
  • Ultrasonography
  • Venous Thrombosis / diagnostic imaging
  • Venous Thrombosis / drug therapy*
  • Venous Thrombosis / physiopathology

Substances

  • Anticoagulants