Abstract
A new jujubogenin saponin was isolated from the stems of Colubrina retusa and identified as jujubogenin 3-O-alpha-L-arabinofuranosyl (1-->2)-[3-O-(trans)-p-coumaroyl-beta-D-glucopyranosyl (1-->3)]-alpha-L-arabinopyranoside (4) on the basis of chemical and spectroscopic data. The antimycobacterial activity expressed as minimum inhibitory concentration (MIC) for compound 4 was 10 microg/mL.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Antitubercular Agents / chemistry
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Antitubercular Agents / isolation & purification*
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Antitubercular Agents / pharmacology
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Carbohydrate Conformation
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Carbohydrate Sequence
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Diterpenes / chemistry
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Diterpenes / isolation & purification*
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Diterpenes / pharmacology
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Magnetic Resonance Spectroscopy
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Mass Spectrometry
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Microbial Sensitivity Tests
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Molecular Sequence Data
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Mycobacterium avium Complex / drug effects
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Oligosaccharides / chemistry
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Oligosaccharides / isolation & purification*
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Oligosaccharides / pharmacology
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Triterpenes*
Substances
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Antitubercular Agents
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Diterpenes
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Oligosaccharides
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Triterpenes
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jujubogenin