Abstract
A second mouse gene related to the nematode mab-21 gene has been isolated. This gene, Mab21l2, encodes a transcript with an open reading frame discretely organized in a single exon. It shares 93.3% and 55.5% amino acid identity with the human and worm mab-21 respectively. FISH analysis determined that this gene is on chromosome 3 at a position between bands 3E3 and 3F1. This newly identified mouse gene will be useful in future examination of mab-21 gene function in vertebrate models.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Animals
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Base Sequence
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Blotting, Southern
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Chromosomes / genetics
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Cloning, Molecular
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DNA, Complementary / genetics
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Exons / genetics
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Expressed Sequence Tags
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Genomic Library
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Homeodomain Proteins / chemistry
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Homeodomain Proteins / genetics*
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Humans
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In Situ Hybridization, Fluorescence
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Mice
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Molecular Sequence Data
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Open Reading Frames / genetics
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Physical Chromosome Mapping*
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RNA, Messenger / analysis
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RNA, Messenger / genetics
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Sequence Alignment
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Sequence Homology, Amino Acid
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Trinucleotide Repeats / genetics
Substances
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DNA, Complementary
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Homeodomain Proteins
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RNA, Messenger