Two DR2-associated novel alleles arose from the silent mutation of codon 72: DRB116012, DRB501012

Tissue Antigens. 1999 Oct;54(4):405-8. doi: 10.1034/j.1399-0039.1999.540411.x.

Authors

Y S Lin¹, T F Tang, J Ng, R Hartzman, C K Hurley

Affiliation

¹ Department of Pediatrics, Georgetown University Medical Center, Washington, DC 20007, USA.

PMID: 10551425
DOI: 10.1034/j.1399-0039.1999.540411.x

Abstract

Two DRB1*02-associated alleles, DRB1*16012 and DRB5*01012, are described. Both alleles carry the same silent substitution at codon 72.

Publication types

Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Alleles
Exons / genetics
HLA-DR Antigens / genetics*
HLA-DR2 Antigen / genetics*
HLA-DRB1 Chains
HLA-DRB5 Chains
Humans
Molecular Sequence Data
Point Mutation*
Sequence Homology, Nucleic Acid

Substances

HLA-DR Antigens
HLA-DR2 Antigen
HLA-DRB1 Chains
HLA-DRB5 Chains

Associated data

GENBANK/U59686
GENBANK/U66721