Abstract
Patients with schizophrenia (DSM IV, n = 149) and controls (n = 180) participated in a case-control association study in which a trinucleotide repeat polymorphism of pancreatic phospholipase A2 group 1B (PLA2G1B) was examined. Both African-American and Caucasian populations were included in this USA sample. There were no significant case-control differences, therefore his study does not support an association between schizophrenia and a PLA2G1B polymorphism on chromosome 12.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adult
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Black People / genetics
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Black or African American
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Case-Control Studies
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Chi-Square Distribution
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DNA / blood
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Female
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Humans
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Male
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Pancreas / enzymology*
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Phospholipases A / genetics*
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Phospholipases A2
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Polymorphism, Genetic*
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Reference Values
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Retrospective Studies
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Schizophrenia / enzymology
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Schizophrenia / genetics*
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Trinucleotide Repeats
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United States
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White People / genetics
Substances
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DNA
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Phospholipases A
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Phospholipases A2