Abstract
We describe a boy with Kawasaki disease (KD) whose clinical course was marked by a rapid improvement upon treatment with intravenous immunoglobulin (IVIG) and oral aspirin, which - within 14 days - was followed by the development of a large pericardial effusion with symptoms of impending cardiac tamponade as part of a polyserositis syndrome (pleural effusions, ascites). Upon treatment with pulsed methylprednisolone, the pericardial and pleural effusions and ascites rapidly disappeared within 48 h. This is the first case reported with a polyserositis syndrome and impending cardiac tamponade during KD.
MeSH terms
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Acute Disease
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Anti-Inflammatory Agents / therapeutic use*
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Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
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Aspirin / therapeutic use
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Cardiac Tamponade / diagnosis
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Cardiac Tamponade / etiology*
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Cardiac Tamponade / prevention & control*
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Child
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Diagnosis, Differential
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Disease Progression
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Drug Administration Schedule
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Echocardiography
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Electrocardiography
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Humans
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Immunoglobulins, Intravenous / therapeutic use
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Male
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Methylprednisolone / therapeutic use*
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Mucocutaneous Lymph Node Syndrome / complications*
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Mucocutaneous Lymph Node Syndrome / drug therapy*
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Mucocutaneous Lymph Node Syndrome / immunology
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Pericardial Effusion / diagnosis
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Pericardial Effusion / etiology*
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Pericardial Effusion / prevention & control*
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Pleural Effusion / diagnosis
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Pleural Effusion / etiology*
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Pleural Effusion / prevention & control*
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Time Factors
Substances
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Anti-Inflammatory Agents
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Anti-Inflammatory Agents, Non-Steroidal
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Immunoglobulins, Intravenous
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Aspirin
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Methylprednisolone