Adjuvant systemic therapy for primary breast cancer

Surg Clin North Am. 1999 Oct;79(5):1075-90. doi: 10.1016/s0039-6109(05)70062-1.

Abstract

Chemotherapy and tamoxifen will continue to play an important role in the treatment of patients with primary breast cancer. Future clinical trials will clarify the role of HDCT for patients at high risk. Molecular markers of response may assist in drug selection in the adjuvant setting. Development of novel therapeutic agents continues based on an expanded biologic understanding of tumor development and progression.

Publication types

  • Review

MeSH terms

  • Antineoplastic Agents, Hormonal / administration & dosage
  • Antineoplastic Agents, Hormonal / therapeutic use*
  • Biomarkers, Tumor / analysis
  • Breast Neoplasms / drug therapy*
  • Breast Neoplasms / etiology
  • Chemotherapy, Adjuvant
  • Disease Progression
  • Drug Design
  • Female
  • Humans
  • Neoadjuvant Therapy
  • Neoplasm Staging
  • Randomized Controlled Trials as Topic
  • Risk Factors
  • Tamoxifen / therapeutic use

Substances

  • Antineoplastic Agents, Hormonal
  • Biomarkers, Tumor
  • Tamoxifen