Abstract
We report an eight-nucleotide duplication in intron 4 of the MICB allele 01021, which was found in samples from different ethnic backgrounds and in association with several HLA-B alleles. We suggest that this new MICB allele is evolutionarily older than HLA-B alleles.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Alleles
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B-Lymphocytes / chemistry
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Base Sequence
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Cell Line
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Ethnicity / genetics
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Evolution, Molecular
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Genes, MHC Class I*
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HLA-B Antigens / genetics
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Histocompatibility Antigens Class I / genetics*
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Humans
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Introns / genetics*
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Linkage Disequilibrium
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Molecular Sequence Data
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Sequence Alignment
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Sequence Homology, Nucleic Acid
Substances
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HLA-B Antigens
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Histocompatibility Antigens Class I
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MICB antigen