Frequencies of defective CYP2C19 alleles in a Hong Kong Chinese population: detection of the rare allele CYP2C19*4

Clin Chem. 1999 Dec;45(12):2273-4.

Authors

M Garcia-Barceló¹, L Y Chow, H F Kum Chiu, Y K Wing, D T Shing Lee, K L Lam, M M Waye

Affiliation

¹ Psychiatry and Biochemistry, The Chinese University of Hong Kong, Hong Kong. [email protected]

PMID: 10585366

No abstract available

Publication types

Comparative Study

MeSH terms

Alleles
Anticonvulsants / metabolism
Aryl Hydrocarbon Hydroxylases*
China / ethnology
Cytochrome P-450 CYP2C19
Cytochrome P-450 Enzyme System / deficiency
Cytochrome P-450 Enzyme System / genetics*
Gene Frequency*
Genotype
Hong Kong
Humans
Isoenzymes / genetics
Mephenytoin / metabolism
Mixed Function Oxygenases / deficiency
Mixed Function Oxygenases / genetics*
Phenotype
Polymorphism, Genetic
Prevalence

Substances

Anticonvulsants
Isoenzymes
Cytochrome P-450 Enzyme System
Mixed Function Oxygenases
Aryl Hydrocarbon Hydroxylases
CYP2C19 protein, human
Cytochrome P-450 CYP2C19
Mephenytoin