Ten percent of North Spanish individuals carry duplicated or triplicated CYP2D6 genes associated with ultrarapid metabolism of debrisoquine

Pharmacogenetics. 1999 Oct;9(5):657-60.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Cytochrome P-450 CYP2D6 / genetics*
  • Cytochrome P-450 CYP2D6 / metabolism*
  • Debrisoquin / metabolism*
  • Female
  • Gene Duplication*
  • Gene Frequency
  • Genotype
  • Humans
  • Male
  • Middle Aged
  • Pharmacogenetics
  • Phenotype
  • Spain

Substances

  • Cytochrome P-450 CYP2D6
  • Debrisoquin