Germline and somatic mutations in von Hippel-Lindau disease gene and its significance in the development of kidney cancer

Contrib Nephrol. 1999:128:1-10. doi: 10.1159/000059976.
No abstract available

Publication types

  • Review

MeSH terms

  • Carcinoma, Renal Cell / genetics*
  • Genes, Tumor Suppressor*
  • Genetic Predisposition to Disease*
  • Humans
  • Kidney Neoplasms / genetics*
  • Ligases*
  • Mutation / genetics
  • Proteins / genetics*
  • Sensitivity and Specificity
  • Tumor Suppressor Proteins*
  • Ubiquitin-Protein Ligases*
  • Von Hippel-Lindau Tumor Suppressor Protein
  • von Hippel-Lindau Disease / genetics*

Substances

  • Proteins
  • Tumor Suppressor Proteins
  • Ubiquitin-Protein Ligases
  • Von Hippel-Lindau Tumor Suppressor Protein
  • Ligases
  • VHL protein, human