Promiscuous origin of a chimeric sequence in the Escherichia coli O157:H7 genome

J Bacteriol. 1999 Dec;181(24):7614-7. doi: 10.1128/JB.181.24.7614-7617.1999.

Abstract

A novel sequence of 2.9 kb in the intergenic region between the mutS and rpoS genes of Escherichia coli O157:H7 and closely related strains replaces a sequence of 6.1 kb in E. coli K-12 strains. At the same locus in Shigella dysenteriae type 1, a sequence identical to that in O157:H7 is bounded by the IS1 insertion sequence element. Extensive polymorphism in the mutS-rpoS chromosomal region is indicative of horizontal transfer events.

MeSH terms

  • Adenosine Triphosphatases*
  • Bacterial Proteins / genetics
  • Base Sequence
  • Chromosome Mapping
  • DNA-Binding Proteins*
  • Escherichia coli O157 / genetics*
  • Escherichia coli Proteins*
  • Genome, Bacterial*
  • Molecular Sequence Data
  • MutS DNA Mismatch-Binding Protein
  • Nucleic Acid Conformation
  • Recombinant Fusion Proteins / genetics
  • Sigma Factor / genetics

Substances

  • Bacterial Proteins
  • DNA-Binding Proteins
  • Escherichia coli Proteins
  • Recombinant Fusion Proteins
  • Sigma Factor
  • sigma factor KatF protein, Bacteria
  • Adenosine Triphosphatases
  • MutS DNA Mismatch-Binding Protein
  • MutS protein, E coli

Associated data

  • GENBANK/AE000357
  • GENBANK/AF054420
  • GENBANK/AF055472
  • GENBANK/U51682