A new germline mutation, R600Q, within the coding region of RET proto-oncogene: a rare polymorphism or a MEN 2 causing mutation?

Hum Mutat. 2000 Jan;15(1):122. doi: 10.1002/(SICI)1098-1004(200001)15:1<122::AID-HUMU41>3.0.CO;2-7.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Amino Acid Substitution
  • Carcinoma, Medullary / genetics*
  • Chromosomes, Human, Pair 10
  • Drosophila Proteins*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Molecular Sequence Data
  • Multiple Endocrine Neoplasia Type 2a / genetics*
  • Mutation, Missense
  • Polymerase Chain Reaction
  • Polymorphism, Single-Stranded Conformational
  • Proto-Oncogene Mas
  • Proto-Oncogene Proteins / genetics*
  • Proto-Oncogene Proteins c-ret
  • Receptor Protein-Tyrosine Kinases / genetics*
  • Thyroid Neoplasms / genetics*

Substances

  • Drosophila Proteins
  • MAS1 protein, human
  • Proto-Oncogene Mas
  • Proto-Oncogene Proteins
  • Proto-Oncogene Proteins c-ret
  • Receptor Protein-Tyrosine Kinases
  • Ret protein, Drosophila

Associated data

  • GENBANK/M57464