Identification of four loci isolated from two Streptococcus thermophilus phage genomes responsible for mediating bacteriophage resistance

E Stanley; L Walsh; A van der Zwet; G F Fitzgerald; D van Sinderen

doi:10.1111/j.1574-6968.2000.tb08907.x

Identification of four loci isolated from two Streptococcus thermophilus phage genomes responsible for mediating bacteriophage resistance

FEMS Microbiol Lett. 2000 Jan 15;182(2):271-7. doi: 10.1111/j.1574-6968.2000.tb08907.x.

Authors

E Stanley¹, L Walsh, A van der Zwet, G F Fitzgerald, D van Sinderen

Affiliation

¹ National Food Biotechnology Centre, University College Cork, Cork, Ireland.

PMID: 10620678
DOI: 10.1111/j.1574-6968.2000.tb08907.x

Abstract

Sequence data derived from the Streptococcus thermophilus phages phiO1205 and phi7201 indicated that each of these phages contains a distinct DNA region dedicated to replication. Southern blotting experiments showed that phages infecting S. thermophilus may be divided into at least two groups, each containing the presumptive replication functions of either φO1205 (group I) or φ7201 (group II). Specific regions from the putative replication module of each of the two phages were examined for their ability to provide phage resistance.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Base Sequence
DNA, Viral / genetics
Molecular Sequence Data
Open Reading Frames / genetics
Plasmids / genetics
Replication Origin / genetics*
Sequence Analysis, DNA
Streptococcus / virology*
Streptococcus Phages / genetics*
Streptococcus Phages / physiology*
Virus Replication

Substances

DNA, Viral