Outcome of psychosis in people of African-Caribbean family origin. Population-based first-episode study

Br J Psychiatry. 1999 Jul:175:43-9. doi: 10.1192/bjp.175.1.43.

Abstract

Background: An increased incidence of psychotic disorders has repeatedly been reported among African-Caribbeans in the UK.

Aims: To test whether the increased incidence of psychotic disorders in first- and second-generation African-Caribbeans in the UK could be caused by a relative excess of affective-related psychoses with good prognosis.

Method: Thirty-three patients of African-Caribbean family origin identified in a population-based study of first-episode psychoses were compared with the remaining cases. Three-year outcomes and patterns of course were compared.

Results: There was a trend for better outcomes in African-Caribbean patients for symptoms and social disability, but patterns of course were similar (odds ratio = 0.9 (0.50 to 2.00)) [corrected]. Pattern of course improved after adjustment for confounding by gender, social class, age, diagnosis and duration of untreated illness (odds ratio = 0.59 (0.21 to 1.66)) [corrected]. Diagnostic profiles were similar, with no evidence of greater diagnostic instability in the African-Caribbean group.

Conclusion: Pattern of course of psychosis did not differ significantly by ethnic family background. An excess of good-prognosis affective psychoses is an unlikely explanation for increased rates of psychosis in African-Caribbeans.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Africa / ethnology
  • Female
  • Follow-Up Studies
  • Humans
  • Incidence
  • Male
  • Mental Health Services / statistics & numerical data
  • Middle Aged
  • Patient Acceptance of Health Care
  • Prognosis
  • Psychotic Disorders / epidemiology
  • Psychotic Disorders / ethnology*
  • United Kingdom / epidemiology
  • West Indies / ethnology