Mixed germ cell tumour of the pineal region: a case report

N Tandon; R Chopra; S Ghoshal; P Singh; B S Sharma

Mixed germ cell tumour of the pineal region: a case report

Neurol India. 1999 Dec;47(4):321-3.

Authors

N Tandon¹, R Chopra, S Ghoshal, P Singh, B S Sharma

Affiliation

¹ Departments of Radiotherapy and Oncology, Neurosurgery and Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.

PMID: 10625909

Abstract

An intracranial mixed germ cell tumour with germinoma and teratoma components is reported. The patient presented with parinaud's syndrome and precocious puberty. The treatment involved partial surgical debulking followed by whole brain radiotherapy (4500 cGY in 25 fraction over 5 weeks) and chemotherapy (consisting of cisplatin and etoposide). Post treatment MRI showed no residual lesion. The controversies in the management are discussed.

Publication types

Case Reports

MeSH terms

Adolescent
Antineoplastic Agents, Phytogenic / therapeutic use
Cisplatin / therapeutic use
Combined Modality Therapy
Etoposide / therapeutic use
Germinoma / drug therapy*
Germinoma / radiotherapy*
Germinoma / surgery
Humans
Male
Pinealoma / drug therapy*
Pinealoma / radiotherapy*
Pinealoma / surgery
Radiation-Sensitizing Agents / therapeutic use
Treatment Outcome

Substances

Antineoplastic Agents, Phytogenic
Radiation-Sensitizing Agents
Etoposide
Cisplatin