Severe factor V deficiency and neonatal intracranial haemorrhage: a case report

Haemophilia. 2000 Jan;6(1):44-6. doi: 10.1046/j.1365-2516.2000.00362.x.

Abstract

We report a case of severe factor V (FV) deficiency (<1%) associated with multiple episodes of intracranial bleeding which presented at birth. The clinical course was further complicated by the development of an inhibitor, episodes of sepsis and cardiac failure. The management using virally inactivated FFP and platelets is discussed.

Publication types

  • Case Reports

MeSH terms

  • Bacterial Infections
  • Blood Coagulation Tests
  • Blood Component Transfusion / adverse effects
  • Developmental Disabilities
  • Diuretics / therapeutic use
  • Factor V / administration & dosage
  • Factor V / immunology
  • Factor V Deficiency / complications*
  • Factor V Deficiency / therapy
  • Family Health
  • Heart Failure / chemically induced
  • Hematoma, Subdural / etiology
  • Humans
  • Hydrocephalus / etiology
  • Hydrocephalus / therapy
  • Immune Tolerance
  • Infant, Newborn
  • Infant, Newborn, Diseases / etiology*
  • Infant, Newborn, Diseases / therapy
  • Intracranial Hemorrhages / etiology*
  • Intracranial Hemorrhages / therapy
  • Isoantibodies / blood
  • Male
  • Pakistan / ethnology
  • Pulmonary Edema / chemically induced
  • United Kingdom

Substances

  • Diuretics
  • Isoantibodies
  • Factor V