Exposure to diagnostic x-rays and incident age-related eye disease

Ophthalmic Epidemiol. 2000 Mar;7(1):61-5.

Abstract

Objective: The purpose of this study was to evaluate whether a self-reported history of computed tomography or other x-rays of the head were associated with the incidence of age-related cataracts and maculopathy five years later.

Method: A 5-year longitudinal follow-up of the Beaver Dam Eye Study cohort (n=3,684, 43-86 years at baseline).

Results: There was no evidence of a relationship between the x-ray exposures and the incidence of nuclear or cortical cataracts, or early maculopathy. There was a significant relationship to the incidence of posterior subcapsular cataract after adjusting for age only.

Conclusions: Adult patients in whom medical conditions warrant diagnostic x-rays of the head appear to be at little or no increased risk of age-related cataract or maculopathy. However, research efforts with more precise measures of x-ray exposure, longer follow-up, and further attempts to define uncontrolled confounders are warranted.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Cataract / epidemiology*
  • Cataract / etiology
  • Cross-Sectional Studies
  • Humans
  • Incidence
  • Lens, Crystalline / radiation effects*
  • Macula Lutea / radiation effects*
  • Macular Degeneration / epidemiology*
  • Macular Degeneration / etiology
  • Middle Aged
  • Radiation Injuries / epidemiology*
  • Radiation Injuries / etiology
  • Retrospective Studies
  • Tomography, X-Ray Computed / adverse effects*
  • Wisconsin / epidemiology