Phase II trial of active immunotherapy of acute myeloid leukemia

Biomedicine. 1975 Sep 10;23(7):291-3.

Abstract

18 acute myeloid leukemia patients were submitted to a Phase II active immunotherapy trial. The median duration of complete remission (CRD) (60 weeks) and of survival after remission (SAR) (104 weeks) were longer than those for our historical control groups. However, the CRD and SAR curves were not broken to form a "cure expectancy" plateau, as was the case for acute lymphoid leukemia.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Antineoplastic Agents / therapeutic use
  • BCG Vaccine*
  • Bone Marrow / immunology*
  • Bone Marrow / radiation effects
  • Bone Marrow Cells*
  • Child
  • Female
  • Humans
  • Leukemia, Myeloid, Acute / immunology
  • Leukemia, Myeloid, Acute / therapy*
  • Male
  • Middle Aged
  • Radiation Effects
  • Remission, Spontaneous

Substances

  • Antineoplastic Agents
  • BCG Vaccine