Abstract
A nine-year-old dog presented with clinical signs consistent with bilateral trigeminal neuropathy. Multicentric lymphoma was diagnosed, and neoplastic lymphocytes were identified in the cerebrospinal fluid. Electromyography revealed spontaneous activity in temporal and masseter muscles. Histopathological examination demonstrated neoplastic cell invasion of temporal and masseter myofibers and of multiple peripheral nerves, including the trigeminal nerve. Central nervous system pathology consisted primarily of spinal root and leptomeningeal lymphoid cell infiltration with relative sparing of spinal cord and brain parenchyma.
MeSH terms
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Animals
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Dog Diseases / cerebrospinal fluid
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Dog Diseases / diagnosis*
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Dogs
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Electromyography / veterinary
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Fatal Outcome
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Female
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Lymphoma, Non-Hodgkin / cerebrospinal fluid
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Lymphoma, Non-Hodgkin / complications
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Lymphoma, Non-Hodgkin / pathology
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Lymphoma, Non-Hodgkin / veterinary*
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Masseter Muscle / pathology
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Masseter Muscle / physiopathology
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Nervous System Neoplasms / cerebrospinal fluid
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Nervous System Neoplasms / complications
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Nervous System Neoplasms / pathology
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Nervous System Neoplasms / veterinary*
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Temporal Muscle / pathology
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Temporal Muscle / physiopathology
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Trigeminal Nerve Diseases / etiology
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Trigeminal Nerve Diseases / veterinary*