The prolonged parenteral nutrition and intestinal transplantation is considered as useful therapeutics for patients with extreme short bowel. However, both of them are still limited. We report the results of nutritional rehabilitation for patients with extreme short bowel. Three patients whose residual intestines were 65 cm, 75 cm and 30 cm respectively were treated with growth hormone, glutamine and a fiber-containing diet for 2-3 weeks. The nutritional status of patients and the absorptive ability of residual intestine in these patients improved obviously after the treatment. This nutritional rehabilitation regime offers a new potential method for patients with short bowel syndrome.