Effects of methotrexate on deoxyribonucleotide pools and nucleic acid synthesis in human osteosarcoma cells

Eur J Cancer (1965). 1976 Oct;12(10):839-45. doi: 10.1016/0014-2964(76)90100-6.
No abstract available

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Bone Marrow / drug effects
  • Bone Marrow Cells
  • Breast Neoplasms / drug therapy
  • Cells, Cultured
  • DNA / biosynthesis*
  • Deoxyribonucleotides / metabolism*
  • Deoxyuridine / metabolism
  • Female
  • Humans
  • Lung Neoplasms
  • Male
  • Methotrexate / blood
  • Methotrexate / pharmacology*
  • Methotrexate / urine
  • Neoplasm Metastasis
  • Osteosarcoma / drug therapy
  • Osteosarcoma / metabolism*
  • RNA / biosynthesis*
  • Time Factors

Substances

  • Deoxyribonucleotides
  • RNA
  • DNA
  • Deoxyuridine
  • Methotrexate