Objective: To investigate the effect and indication of mifepristone in treating ectopic pregnancy, 47 patients were divided into three groups.
Results: Twenty-nine cases were effective; 18 cases were ineffective and operated on in which we observed the gestational termination, bleeding capacity, and pathological changes in fallopian tube. We found that the effect was related to the drug dosage, levels of beta-hCG in blood and the operating time.
Conclusion: High dosage of mifepristone in treating ectopic pregnancy is convenient, safe, and has no side-effects. It is suitable for patients with early ectopic pregnancy who have smooth life-sign, beta-hCG < 10 ng.ml-1, the mass in pelvic cavity < or = 5 cm, without acute belly-ache and pulsation of fetal heart in fallopian tube and who ask for the conservative treatment.