[Effects of fat emulsion on serum lipid, apo A I, apo B100, LCAT, KBR of postoperative patients with liver disorder]

Hua Xi Yi Ke Da Xue Xue Bao. 1998 Jun;29(2):209-212.
[Article in Chinese]

Abstract

Twenty post-operative patients with liver disorder were divided randomly into two groups. Ten of them received mean 0.82 g.kg-1.d-1 fat emulsion(42% of the total calorie), and the other ten received mean 1.72 g.kg-1.d-1 fat emulsion (52% of the total calorie) via vein during 5 post-operative days. Their serum lipid, apoA I, apoB100, ketone body ratio (KBR), fat clearance, LCAT and so on were investigted. The results suggest that it is safe for liver-disordered patients with slight or even moderate abnormality of liver function to receive mean 0.82 g.kg-1.d-1 and 1.72 g.kg-1.d-1 fat emulsion after operation and the use of mean 1.72 g.kg-1.d-1 fat emulsion will do no harm but good to liver function.

Publication types

  • Clinical Trial
  • English Abstract
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Apolipoprotein A-I / blood*
  • Apolipoprotein B-100
  • Apolipoproteins B / blood
  • Carcinoma, Hepatocellular / blood
  • Carcinoma, Hepatocellular / surgery
  • Carcinoma, Hepatocellular / therapy
  • Cholesterol / blood*
  • Fat Emulsions, Intravenous / adverse effects
  • Fat Emulsions, Intravenous / therapeutic use
  • Female
  • Humans
  • Hypertension, Portal / blood*
  • Hypertension, Portal / surgery
  • Hypertension, Portal / therapy
  • Ketones / blood
  • Liver Neoplasms / blood
  • Liver Neoplasms / surgery
  • Liver Neoplasms / therapy
  • Male
  • Middle Aged
  • Phosphatidylcholine-Sterol O-Acyltransferase / blood*
  • Postoperative Period
  • Triglycerides / blood

Substances

  • Apolipoprotein A-I
  • Apolipoprotein B-100
  • Apolipoproteins B
  • Fat Emulsions, Intravenous
  • Ketones
  • Triglycerides
  • Cholesterol
  • Phosphatidylcholine-Sterol O-Acyltransferase