Deep vein thrombosis prophylaxis in hip fractures: a comparison of the arteriovenous impulse system and aspirin

J Trauma. 2000 Feb;48(2):268-72. doi: 10.1097/00005373-200002000-00012.

Abstract

Background: A prospective, randomized controlled trial was used to compare the efficacy of the arteriovenous (AV) impulse system and aspirin in reducing venous thrombosis after fracture to the femoral neck.

Methods: A total of 143 patients underwent hemiarthroplasty, after which 70 patients were treated with the AV pump and a second group of 73 patients were commenced on 325 mg of aspirin. Duplex ultrasound was used to assess both proximal and distal venous thrombi on days 7 to 10. Calf and thigh circumferences were also measured.

Results: Thrombi developed in seven of the patients treated with aspirin and in four patients treated with the AV pump. No statistically significant difference could be established (p = 0.109). There was a significant reduction in both calf (p = 0.003) and thigh (p = 0.002) swelling in the group treated with the AV pump. Neither treatment group was a significant predictor of a poorer outcome by using logistical regression analysis (p = 0.258).

Conclusions: Both aspirin and the AV pump are effective in reducing thromboembolic events after hemiarthroplasty of the hip.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Aged
  • Aspirin / therapeutic use*
  • Cardiology / instrumentation
  • Female
  • Femoral Neck Fractures / complications*
  • Humans
  • Leg / blood supply
  • Male
  • Platelet Aggregation Inhibitors / therapeutic use*
  • Prospective Studies
  • Venous Thrombosis / etiology*
  • Venous Thrombosis / prevention & control*

Substances

  • Platelet Aggregation Inhibitors
  • Aspirin