Identification of a novel single nucleotide polymorphism (SNP) in the human organic cation transporter-like 2-antisense (ORCTL2S) gene

K Higashimoto; H Soejima; T Katsuki; T Mukai

doi:10.1007/s100380050012

Identification of a novel single nucleotide polymorphism (SNP) in the human organic cation transporter-like 2-antisense (ORCTL2S) gene

J Hum Genet. 2000;45(1):58-9. doi: 10.1007/s100380050012.

Authors

K Higashimoto¹, H Soejima, T Katsuki, T Mukai

Affiliation

¹ Department of Biochemistry, Saga Medical School, Japan.

PMID: 10697966
DOI: 10.1007/s100380050012

Abstract

We found a single nucleotide polymorphism (SNP) in exon 3 of the human organic cation transporter-like 2-antisense (ORCTL2S) gene: a base substitution A266G which was confirmed by direct sequencing. Heterozygosity of the polymorphic alleles was 0.45 in a Japanese population. This polymorphism will be useful in the allelic expression analysis of the ORCTL2S gene.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Carrier Proteins / genetics*
Chromosomes, Human, Pair 11
DNA, Antisense
Exons
Gene Frequency
Humans
Japan / epidemiology
Membrane Proteins / genetics*
Mutation, Missense
Organic Cation Transport Proteins*
Polymorphism, Single Nucleotide

Substances

Carrier Proteins
DNA, Antisense
Membrane Proteins
Organic Cation Transport Proteins
SLC22A18 protein, human
SLC22A18AS protein, human