Detection of four novel alleles: DRB1*1130, DRB1*13072, DRB1*1315 and DRB1*1331

Y S Lin; R J Hoyer; T F Tang; J Ng; R J Hartzmann; C K Hurley

doi:10.1034/j.1399-0039.2000.550121.x

Detection of four novel alleles: DRB11130, DRB113072, DRB11315 and DRB11331

Tissue Antigens. 2000 Jan;55(1):92-6. doi: 10.1034/j.1399-0039.2000.550121.x.

Authors

Y S Lin¹, R J Hoyer, T F Tang, J Ng, R J Hartzmann, C K Hurley

Affiliation

¹ Department of Pediatrics, Georgetown University Medical Center, Washington, DC 20007, USA.

PMID: 10703621
DOI: 10.1034/j.1399-0039.2000.550121.x

Abstract

Four new DR52-associated DRB1 alleles are described. One allele, DRB1*1130, is a hybrid between a DRB3*02 allele and a DRB1*11011 allele. The other alleles, DRB1*13072, DRB1*1315, and DRB1*1331, are simple reshufflings of known polymorphic motifs.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Alleles*
Base Sequence
DNA Primers / chemistry
Gene Conversion
HLA-DR Antigens / genetics*
HLA-DRB1 Chains
Humans
Molecular Sequence Data
Racial Groups / genetics
Sequence Analysis, DNA
Sequence Homology, Nucleic Acid

Substances

DNA Primers
HLA-DR Antigens
HLA-DRB1 Chains
HLA-DRB1*11:01:01 antigen

Associated data

GENBANK/AF036944
GENBANK/U32325
GENBANK/U79027
GENBANK/U88133
GENBANK/U88134