Tolerability and side-effects of post-exposure prophylaxis for HIV infection

Lancet. 2000 Feb 26;355(9205):722-3. doi: 10.1016/s0140-6736(99)05005-9.

Abstract

A study of HIV post-exposure prophylaxis in 28 recipients showed that indinavir-containing regimens were poorly tolerated. This finding has implications for compliance and efficacy of the currently recommended combinations.

Publication types

  • Letter

MeSH terms

  • Anti-HIV Agents / adverse effects*
  • Drug Combinations
  • Drug Tolerance
  • HIV Infections / prevention & control*
  • HIV Protease Inhibitors / adverse effects*
  • HIV-1*
  • Humans
  • Indinavir / adverse effects*
  • Lamivudine / adverse effects
  • London
  • Needlestick Injuries*
  • Patient Compliance
  • Personnel, Hospital
  • Retrospective Studies
  • Zidovudine / adverse effects

Substances

  • Anti-HIV Agents
  • Drug Combinations
  • HIV Protease Inhibitors
  • Lamivudine
  • Zidovudine
  • Indinavir