Allelic distribution of nine short tandem repeat (STR), HLA-DQA1, and polymarker loci in an Omani sample population

Forensic Sci Int. 2000 Mar 27;109(2):81-5. doi: 10.1016/s0379-0738(99)00227-3.

Abstract

Allele frequency distributions of nine short tandem repeat (STR) loci, D3S1358, vWA, FGA, D8S1179, D21S11, D18S51, D5S818, D7S820, and D13S317, HLA-DQA1 and polymarker (PM) loci were studied in a sample population from Sultanate of Oman, Middle East. Blood samples were collected from 162 unrelated individuals. For all STR, HLA-DQA1 and PM loci, no deviations from Hardy-Weinberg equilibrium, based on the exact test, were observed. The most discriminating loci were D18S51 (PD=0.966) and FGA (PD=0.964), while the least informative locus is GYPA (PD=0.585). The allele frequency data may be useful in forensic case work.

MeSH terms

  • Alleles*
  • DNA Fingerprinting / methods
  • Discriminant Analysis
  • Gene Frequency / genetics*
  • Genetic Markers / genetics
  • HLA-DQ Antigens / genetics*
  • HLA-DQ alpha-Chains
  • Homozygote
  • Humans
  • Minisatellite Repeats / genetics*
  • Oman
  • Polymorphism, Genetic / genetics
  • Reproducibility of Results

Substances

  • Genetic Markers
  • HLA-DQ Antigens
  • HLA-DQ alpha-Chains
  • HLA-DQA1 antigen