Furoquinolines with antiplatelet aggregation activity from leaves of Melicope confusa

K S Chen; Y L Chang; C M Teng; C F Chen; Y C Wu

doi:10.1055/s-0029-1243116

Furoquinolines with antiplatelet aggregation activity from leaves of Melicope confusa

Planta Med. 2000 Feb;66(1):80-1. doi: 10.1055/s-0029-1243116.

Authors

K S Chen, Y L Chang, C M Teng, C F Chen, Y C Wu

PMID: 10705744
DOI: 10.1055/s-0029-1243116

Abstract

Using antiplatelet aggregation as a guide for fractionation, four furoquinoline-type alkaloids, confusameline (1), skimmianine (2), kokusaginine (3), and O-methylconfusameline (4), were isolated from the leaves of Melicope confusa. All compounds showed significant antiplatelet aggregation activity.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
In Vitro Techniques
Plant Leaves / chemistry
Plants, Medicinal / chemistry*
Platelet Aggregation Inhibitors / pharmacology*
Quinolines / pharmacology*
Rabbits
Trees / chemistry

Substances

Platelet Aggregation Inhibitors
Quinolines