Abstract
There are many treatment methods for lupus nephritis, including high-dose steroids, pulse methylprednisolone, and cyclophosphamide therapy. In cyclophosphamide therapy, there can be some side effects such as nausea, vomiting, and infection. We report on a case receiving a combination of high dose steroid and intravenous cyclophosphamide. Following this, she developed a fever and a protruding right eye, and septic cavernous sinus thrombosis was diagnosed. This complication had never been reported in a patient with systemic lupus erythematosus, and related literature is reviewed.
MeSH terms
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Adult
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Cavernous Sinus Thrombosis / chemically induced*
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Cyclophosphamide / adverse effects*
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Cyclophosphamide / therapeutic use
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Drug Therapy, Combination
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Exophthalmos / chemically induced
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Exophthalmos / diagnostic imaging
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Female
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Glucocorticoids / adverse effects*
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Glucocorticoids / therapeutic use
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Humans
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Immunosuppressive Agents / adverse effects*
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Immunosuppressive Agents / therapeutic use
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Infusions, Intravenous
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Lupus Nephritis / drug therapy*
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Prednisolone / adverse effects*
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Prednisolone / therapeutic use
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Tomography, X-Ray Computed
Substances
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Glucocorticoids
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Immunosuppressive Agents
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Cyclophosphamide
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Prednisolone