Length of time to laboratory diagnosis of Mycobacterium tuberculosis infection: comparison of in-house methods with reference laboratory results

J Infect. 1999 Nov;39(3):205-8. doi: 10.1016/s0163-4453(99)90050-6.

Abstract

Objectives: To audit the time taken to obtain laboratory confirmation of infection with Mycobacterium tuberculosis using in-house methods of polymerase chain reaction (PCR) and culture and referral to a reference laboratory.

Methods: Retrospective collection of data from laboratory records covering a period of 1 year.

Results: Median time to microbiological diagnosis of a new infection using the in-house services in addition to the reference laboratory was 22.0 days. Using reference laboratory results alone, median time to diagnosis would have been 61.5 days.

Conclusions: Development of on-site laboratory facilities to identify Mycobacterium tuberculosis can reduce the time to its identification by almost two-thirds.

Publication types

  • Comparative Study

MeSH terms

  • Clinical Laboratory Techniques
  • Humans
  • Mycobacterium tuberculosis / isolation & purification
  • Polymerase Chain Reaction
  • Time Factors
  • Tuberculosis / diagnosis*