[Value of negative oral contrast media in MR cholangiopancreatography (MRCP)]

Rofo. 2000 Jan;172(1):55-60. doi: 10.1055/s-2000-11100.
[Article in German]

Abstract

Purpose: Evaluation of the use of a negative oral contrast material in MR cholangiopancreatography (MRCP).

Material and methods: We performed MRCP in single-shot technique (TSE, TR = 2800 ms, TE = 1100 ms, ETL = 64) in 38 patients before and 20-30 min after oral administration of 300-600 ml of a negative oral contrast material. The visualization ducts and details important for the diagnosis was evaluated in a blinded manner. Ductal diameters were measured. Both sets of images were evaluated qualitatively.

Results: The ductal diameters did not change after administration of oral contrast material. In 1/3 of all cases the ductal structures were superimposed by a high signal intensity of fluid in the gastrointestinal tract, especially in the tail of the pancreas. After administration of oral contrast material only in 3 patients could a complete visualization of the ducts not be achieved. In 5 cases, details relevant for the diagnostic decision could be seen only on post-contrast images. The anatomic orientation was not compromised by the absence of signal in the gastrointestinal tract.

Conclusion: Negative oral contrast material should be given before performing a MRCP to provide non-superimposed visualization of the bile and pancreatic ducts. There is no negative influence of the oral contrast material on the diameter of the ducts.

MeSH terms

  • Administration, Oral
  • Adult
  • Aged
  • Bile Ducts / pathology
  • Cholangitis, Sclerosing / diagnosis*
  • Cholelithiasis / diagnosis*
  • Contrast Media* / adverse effects
  • Female
  • Ferrosoferric Oxide
  • Humans
  • Iron* / adverse effects
  • Liver / pathology
  • Liver Neoplasms / diagnosis*
  • Magnetic Resonance Imaging*
  • Magnetite Nanoparticles
  • Male
  • Middle Aged
  • Oxides* / adverse effects
  • Pancreas / pathology
  • Pancreatic Neoplasms / diagnosis*
  • Pancreatitis / diagnosis*
  • Reference Values
  • Sensitivity and Specificity
  • Siloxanes* / adverse effects

Substances

  • Contrast Media
  • Magnetite Nanoparticles
  • Oxides
  • Siloxanes
  • ferumoxsil
  • Iron
  • Ferrosoferric Oxide