Abstract
Human immunodeficiency virus (HIV)-infected, active intravenous drug users received once-daily therapy consisting of a combination of didanosine (2',3'-dideoxyinosine or DDI), lamivudine [(-)-beta-L-2',3'-dideoxy-3'-thiacytidine or 3TC] and nevirapine. Preliminary results for the first 24 weeks show that the regimen provides potent immunological and antiviral effects.
MeSH terms
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Adult
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CD4 Lymphocyte Count
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Didanosine / administration & dosage*
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Drug Therapy, Combination
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Female
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HIV Infections / complications
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HIV Infections / drug therapy*
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HIV-1*
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Humans
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Lamivudine / administration & dosage*
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Male
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Methadone / therapeutic use
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Nevirapine / administration & dosage*
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Pilot Projects
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Prospective Studies
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Substance Abuse, Intravenous / complications*
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Substance Abuse, Intravenous / drug therapy
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Viral Load
Substances
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Lamivudine
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Nevirapine
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Didanosine
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Methadone