Role of Kupffer cells and oxidants in signaling peroxisome proliferator-induced hepatocyte proliferation

Mutat Res. 2000 Mar 17;448(2):179-92. doi: 10.1016/s0027-5107(99)00235-3.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Cell Division / drug effects
  • Enzyme Activation
  • Glycine / metabolism
  • Humans
  • Kupffer Cells / drug effects
  • Kupffer Cells / physiology*
  • Liver / drug effects*
  • Liver / metabolism
  • Liver Neoplasms / chemically induced
  • Liver Neoplasms / pathology
  • NF-kappa B / metabolism
  • Oxidants / physiology*
  • Palmitates / metabolism
  • Palmitates / pharmacology
  • Peroxisome Proliferators / toxicity*
  • Protein Kinase C / metabolism
  • Pyrimidines / metabolism
  • Pyrimidines / pharmacology
  • Signal Transduction*
  • Superoxides / metabolism

Substances

  • NF-kappa B
  • Oxidants
  • Palmitates
  • Peroxisome Proliferators
  • Pyrimidines
  • Superoxides
  • pirinixic acid
  • methyl palmitate
  • Protein Kinase C
  • Glycine