Ovarian dysgerminoma with massive metastases to para-aortic lymph nodes

Gynecol Obstet Invest. 2000;49(3):211-3. doi: 10.1159/000010249.

Abstract

We report on a 15-year-old female with left ovarian dysgerminoma accompanied by massive swelling of the para-aortic lymph nodes which was clearly demonstrated by preoperative magnetic resonance imaging (MRI). Metastasis to the para-aortic lymph nodes from dysgerminoma was confirmed by biopsies obtained during surgery. No study has previously reported dysgerminoma with massive para-aortic lymph node metastases clearly demonstrated by MRI. These preoperative MRI findings are presented here. The patient received six cycles of cisplatin-based combination chemotherapy with the BEP regimen (bleomycin, etoposide and cisplatin) after conservative surgery, and no residual para-aortic lymph nodes were detected by MRI or CT after the chemotherapy.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Aorta
  • Biopsy
  • Bleomycin / administration & dosage
  • Cisplatin / administration & dosage
  • Dysgerminoma / drug therapy
  • Dysgerminoma / pathology
  • Dysgerminoma / secondary*
  • Dysgerminoma / surgery
  • Etoposide / administration & dosage
  • Female
  • Humans
  • Lymphatic Metastasis*
  • Magnetic Resonance Imaging
  • Ovarian Neoplasms / drug therapy
  • Ovarian Neoplasms / pathology*
  • Ovarian Neoplasms / surgery

Substances

  • Bleomycin
  • Etoposide
  • Cisplatin

Supplementary concepts

  • BEP protocol