Abstract
Schizophrenia is often associated with cognitive deficits, particularly within the domains of memory and language. Specific cognitive deficits have recently been linked to psychotic phenomena, including verbal hallucinations and disorganized speech. Impairments of working and semantic memory are primarily due to dysfunction of the frontal cortex, temporal cortex, and hippocampus. Cognitive skills in schizophrenia predict social functioning and may serve as outcome measures in the development of effective treatment strategies.
MeSH terms
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Brain Mapping
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Cognition Disorders / complications
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Cognition Disorders / drug therapy
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Cognition Disorders / physiopathology*
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Frontal Lobe / physiopathology
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Hallucinations / etiology
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Hallucinations / physiopathology
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Hippocampus / physiopathology
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Humans
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Memory Disorders / etiology
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Memory Disorders / physiopathology
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Psychotropic Drugs / adverse effects
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Psychotropic Drugs / therapeutic use
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Schizophrenia / complications
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Schizophrenia / drug therapy
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Schizophrenia / physiopathology*
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Social Adjustment
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Speech Disorders / etiology
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Speech Disorders / physiopathology
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Temporal Lobe / physiopathology