Isolation of psammaplin A 11'-sulfate and bisaprasin 11'-sulfate from the marine sponge Aplysinella rhax

N B Pham; M S Butler; R J Quinn

doi:10.1021/np990335y

Isolation of psammaplin A 11'-sulfate and bisaprasin 11'-sulfate from the marine sponge Aplysinella rhax

J Nat Prod. 2000 Mar;63(3):393-5. doi: 10.1021/np990335y.

Authors

N B Pham¹, M S Butler, R J Quinn

Affiliation

¹ Queensland Pharmaceutical Research Institute, Griffith University, Brisbane, Australia 4111.

PMID: 10757728
DOI: 10.1021/np990335y

Abstract

Psammaplin A 11'-sulfate (3) and bisaprasin 11'-sulfate (4) have been isolated from the marine sponge Aplysinella rhax, along with the known psammaplin A (1). Their structures were determined on the basis of their spectroscopic data. Compounds 1 and 3 inhibited [(3)H]1,3-dipropyl-8-cyclopentylxanthine binding to rat-brain adenosine A(1) receptors.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Molecular Structure
Porifera / chemistry*
Rats
Spectrum Analysis
Sulfuric Acid Esters / chemistry
Sulfuric Acid Esters / isolation & purification*
Tyrosine / analogs & derivatives*
Tyrosine / chemistry
Tyrosine / isolation & purification

Substances

Sulfuric Acid Esters
bisaprasin 11'-sulfate
Tyrosine