[Proctocolectomy with an ileal pouch-anal anastomosis; results from 100 consecutive patients in the Academic Medical Center at Amsterdam, 1994-1999]

Ned Tijdschr Geneeskd. 2000 Mar 25;144(13):612-6.
[Article in Dutch]

Abstract

Objective: To evaluate the results of proctocolectomy with creation of an ileac pouch anal anastomosis (IPAA).

Design: Retrospective.

Method: Of the 100 patients in whom an IPAA procedure was performed in the period 1994/'99 in the Department of Surgery of the Academic Medical Centre, Amsterdam, the Netherlands, data were collected on the complications: in the patients with a follow-up of over 12 months the functional results were studied.

Results: The group comprised 48 males and 52 females with a mean age of 36.3 years (range: 15-62). Preoperative diagnoses were ulcerative colitis (n = 84), familial polyposis coli (12), slow transit obstipation (2), Hirschsprung's disease (1) and Muir-Torre syndrome (1). Median operating time was 2.3 h, peroperative blood and fluid loss 500 ml and median hospital stay 15 days. There was no mortality. Ten patients had a loop ileostomy formation, in 6 because of postoperative complications. A total of 30 patients developed postoperative complications, peroperatively or during follow-up 10 of those patients needed a relaparotomy. After 12 months 1 pouch had to be excised and 2 patients still had a loop ileostomy due to postoperative complications. In 56 patients with at least 12 months follow-up, median 24-hour stool frequency was 6. Eighty-nine per cent of these patients were satisfied or highly satisfied with the overall outcome.

Conclusion: A proctocolectomy with IPAA formation is a safe procedure with good functional results.

Publication types

  • English Abstract

MeSH terms

  • Adenocarcinoma / surgery
  • Adenomatous Polyposis Coli / surgery
  • Adolescent
  • Adult
  • Colitis, Ulcerative / surgery
  • Colonic Diseases / surgery*
  • Colonic Neoplasms / surgery
  • Female
  • Follow-Up Studies
  • Hirschsprung Disease / surgery
  • Humans
  • Male
  • Middle Aged
  • Patient Satisfaction
  • Proctocolectomy, Restorative* / adverse effects
  • Proctocolectomy, Restorative* / methods
  • Reoperation
  • Retrospective Studies
  • Sampling Studies
  • Treatment Outcome